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MedlinePlus Connect found the following health information for your request. Always consult your health care provider about your specific situation.
Methotrexate is used to treat severe psoriasis (a skin disease in which red, scaly patches form on some areas of the body) that cannot be controlled by other treatments. Methotrexate is also used along with rest, physical therapy, and sometimes other medications to treat severe active rheumatoid arthritis (RA; a condition in which the body attacks its own joints, causing pain, swelling, and loss... https://medlineplus.gov/druginfo/meds/a682019.html
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